hrp0089p1-p210 | Pituitary, Neuroendocrinology and Puberty P1 | ESPE2018

Hypothalamic-pituitary-testicular Axis Response to Sub-maximal Aerobic Exercise, in Pre- and Early- Pubertal Normal Weight and Obese Boys

Paltoglou George , Avloniti Alexandra , Chatzinikolaou Athanasios , Mantzou Aimilia , Stefanaki Charikleia , Papagianni Maria , Fatouros Ioannis , Mastorakos Ge

Objective: To investigate the association of the gonadal axis with pro- and anti- oxidation, in relation to obesity and pubertal status in boys, before and after a stimulatory exercise bout.Design: Cross-sectional human experimental study.Methods: Ninty-two healthy normal-weight and obese pre- and early- pubertal boys, participated in this study. All subjects underwent a baseline blood sampling followed by an aerobic exercise bout ...

hrp0084p2-427 | GH & IGF | ESPE2015

rhGH Replacement Therapy Ameliorates Body Composition Substantially but has No Effect in the Quality of Life in Adolescents with GH deficiency – A Cross-Sectional Study

Stefanaki Charikleia , Paltoglou George , Bacopoulou Flora , Boschiero Dario , Chrousos George P

Background: GH is fundamental in skeletal growth during puberty, however detailed studies of body composition analyses in adolescents with GH deficiency on GH therapy are scarce. Moreover, there are few studies on the psychologic aspects of hrGH therapy in this population.Objective and hypotheses: In this case-control study, we investigated differences in body composition based on bio-impedance measurements between adolescents with idiopathic GH deficien...

hrp0084p2-181 | Adrenals | ESPE2015

Baseline Cortisol Concentrations Predict Positively and Negatively Anti- and Pro- Oxidation, Respectively that are Measured Following an Acute Aerobic Exercise Bout in Pre- and Early Pubertal Normal-Weight and Obese Boys

Paltoglou George , Papagianni Maria , Fatouros Ioannis G. , Mantzou Aimilia , Jamurtas Athanasios , Avloniti Alexandra , Stefanaki Charikleia , Kanaka-Gantenbein Christina , Chrousos George P. , Mastorakos George

Background: Little data exist regarding the hypothalamic-pituitary-adrenal (HPA) axis activation and the interplay between the HPA axis and markers of pro- and anti-oxidation in children, following an acute aerobic exercise bout in children.Objective and hypotheses: To investigate the changes of HPA axis hormones following an acute bout of aerobic exercise and their respective association with markers of pro- and anti- oxidation in normal weight and obes...